Three main side effects of Invokana you should know


Invokana is part of a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors which has seen a huge response in the treatment of adults with type 2 diabetes. Type 2 diabetes is a disease in which a person has high levels of sugar in his or her blood, when the pancreas fails to create enough of insulin and regulate blood sugar. Invokana is manufactured by Janssen Pharmaceuticals, Inc., (a division of Johnson & Johnson) is supposed to help patients achieve glycemic control.


 Unfortunately, there have been reports which suggest otherwise. The patients with diabetic complications led patients developing kidney injury and kidney failure, diabetic ketoacidosis, and toe, foot, or leg amputations after taking the drug.
The following are the main side effects of invokana:

The kidneys are a vital component in the workings of Invokana, but the drug can develop reduced kidney function or kidney failure. When this occurs, the kidneys are unable to filter out waste, resulting in numerous complications, including fatal consequences. Many people can end up requiring a kidney transplant or ongoing dialysis to restore the waste-elimination function in the body.
Ketoacidosis is a condition associated with diabetes in which a person’s body produces high levels of blood acids called ketones. When the body does not have enough insulin, the muscles are prevented from using glucose for energy and instead break down fat for energy. The fat breakdown releases ketones into the bloodstream, which can start to build up. Symptoms of ketoacidosis can appear within 24 hours and include:

Patients taking Invokana are at an increased significant risk for requiring amputations of their feet, toes, and sometimes legs.
Diabetic patients are already at risk of feet and lower limb issues but with the drug, it can lead to tissue damage and death (also known as gangrene). These amputations have a tremendous effect on people’s lives, as they deal not only with extreme pain but might need prostheses, and potential phantom limb sensations.

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